The best Pandemic games and variants⎇ 2025

Pandemic Legacy: Season 1 offers an extraordinary gaming experience as a cooperative campaign game, immersing players in an overarching story-arc that unfolds over 12-24 gripping sessions. The duration depends on your group's performance and the fate of the world. Here's an overview of this thrilling journey:

Pandemic: On the Brink is an expansion for the popular cooperative board game Pandemic. This expansion adds new dimensions to the base game, offering additional challenges and variability in gameplay.

Pandemic: Iberia is a historical variant of the popular Pandemic series, set in the Iberian Peninsula during the year 1848. This version of the game introduces unique roles and challenges as players work together to combat historical diseases like malaria, typhus, yellow fever, and cholera.

Pandemic is a highly acclaimed cooperative board game where players take on the roles of disease-fighting specialists. Their mission is to contain and cure four deadly diseases that have broken out across the globe. The game is set on a board depicting major world population centers and requires players to strategize and work together to manage the outbreaks and develop cures before the diseases spiral out of control.

Pandemic Legacy: Season 0 transports you to 1962, at the height of the Cold War, where a mysterious Soviet bioweapon called "Project MEDUSA" threatens global safety. As newly recruited CIA agents and medical graduates, you and your team are tasked with a critical mission: investigate and halt the development of this deadly pathogen. This game stands alone as a thrilling prequel to the earlier seasons of Pandemic Legacy, immersing players in a tense world of espionage and covert operations.

Traverse a galaxy where iconic Jedi heroes utilize familiar Pandemic mechanics. Players assume the roles of legendary Jedi, joining forces to combat the threat posed by the Separatists while defending besieged planets. They must work together to fend off droid assaults, conquer blockades, complete missions, and face iconic villains to turn the tide of war.

Pandemic: Reign of Cthulhu is a thrilling adaptation of the classic Pandemic game, infused with a chilling Lovecraftian theme. Players take on the roles of investigators, tasked with a daunting mission to prevent the awakening of ancient evils, known as Old Ones, from their cosmic prison.

Pandemic: The Cure is a dice-based adaptation of the popular Pandemic board game. It offers a quicker setup and playtime while retaining the core theme of disease control and teamwork.

Pandemic: Fall of Rome is a unique cooperative board game that blends the classic gameplay of Pandemic with the historical setting of the Roman Empire's decline. In this game, players work together as citizens, soldiers, and allies of Rome, tasked with defending the empire against various barbarian tribes like the Anglo-Saxons, Goths, Vandals, and Huns. The game requires players to strategically recruit armies, fortify cities, and forge alliances to halt the onslaught of invaders.

Unlock! Game Adventures brings the thrill of escape rooms to the tabletop, combining the enigmatic puzzles and cooperative gameplay of the Unlock! series with the universes of three iconic board games. This expansion introduces a trio of scenarios, each immersing players in the worlds of Mysterium, Ticket to Ride, and Pandemic, offering unique challenges that blend the mechanics and themes of these beloved games with the puzzle-solving and teamwork of escape rooms.

Pandemic Legacy: Season 2 is an epic, cooperative board game that continues the narrative and innovative gameplay of its predecessor. This game is set in a post-apocalyptic world where humanity struggles to survive after a devastating plague. It offers a unique gaming experience, where players' decisions and actions have long-lasting consequences, making each playthrough distinct.

Pandemic: The Cure – Experimental Meds is an expansion for Pandemic: The Cure, the dice-based version of the popular cooperative game Pandemic. This expansion introduces significant new challenges and elements that add depth and complexity to the base game, providing fresh gameplay experiences and increased replayability.

Players travel to the frozen continent of Northrend to confront the armies of the Lich King in this "Pandemic System" game, adapted to fit the setting of Wrath of the Lich King. They take on the roles of legendary heroes from Azeroth, such as Thrall and Varian Wrynn, each with unique abilities to aid in and out of battle. Players complete quests and fight against hordes of undead while facing dark magic and terrifying creatures in their quest to reach the Icecrown Citadel for a final showdown.

Pandemic: In the Lab is the second expansion for the popular cooperative game Pandemic, introducing a unique laboratory setting where players engage in scientific research to find cures for diseases. This expansion adds a new layer of strategy and thematic depth, requiring the base game to play, and in some cases, the first expansion, Pandemic: On the Brink.

Pandemic: Hot Zone – North America is a streamlined, cooperative board game that condenses the thrilling experience of the classic Pandemic into a quicker and more portable format. In this version, players unite to combat the spread of three deadly diseases across North America, racing against time to prevent outbreaks and find cures.

Pandemic: Rising Tide is a thematic and cooperative board game that immerses players in the historical context of the Netherlands during the Industrial Age. The game challenges players to manage and mitigate flooding from the North Sea using innovative hydraulic technologies, strategic planning, and teamwork.

Pandemic: Hot Zone – Europe is a compact and quick-playing version of the beloved cooperative game Pandemic. Set against the backdrop of Europe, this iteration maintains the core mechanics of the original game but in a streamlined format that's ideal for players looking for a shorter game time and greater portability.

Pandemic: State of Emergency is an expansion for the renowned cooperative game Pandemic, introducing new layers of complexity and strategic challenges that heighten the game's intensity and realism. This expansion adds three distinct challenges that test players' ability to manage and contain outbreaks under increasingly difficult circumstances.

In Pandemic: Contagion, the tables are turned from the classic Pandemic formula—instead of curing diseases, players become the diseases themselves, vying to outpace each other in a grim race to eradicate humanity. This standalone game flips the script on the cooperative nature of its predecessors, offering a competitive gameplay experience where the deadliest pathogen wins. With no cure in sight, players strategize to spread their contagion far and wide, mutating and evolving to become increasingly lethal.

Pandemic: Rapid Response is a thrilling, real-time cooperative game that transforms players into members of the Crisis Response Unit (CRU), tasked with delivering essential supplies to cities worldwide amid catastrophic disasters. This high-stakes version of Pandemic introduces a time-sensitive gameplay dynamic that emphasizes quick decision-making and effective team coordination.